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´╗┐Cancer Gene Therapy Advance

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tumor cells. The main drawback, so far, is that Advexin must be injected directly into tumor cells.

Their study enrolled 123 patients with recurrent squamous cell carcinoma of the head and neck whose cancers did not respond to first line treatment. Because such cancers are almost always fatal, patients received either Advexin or chemotherapy with

Fortunately, there's a test to see which patients are most likely to respond to Advexin. But Nemunaitis says that if Advexin can help patients with the most severe form of cancer, it can do a lot more for patients treated at earlier stages of disease.

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May 30, 2008 Advexin, a genetically Nike Air Max All White

And since Advexin has far fewer side effects than traditional chemotherapy cold like fever and chills were the main side effects combination therapy with the drug may be more tolerable than other combination chemotherapies.

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Nemunaitis says it's likely that in the future, Advexin will probably have to be combined with other forms of chemotherapy to maximize its effect.

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"As a doctor, I talk with patients and just being able to offer them several months is frustrating," he tells WebMD. "But we have some patients out nine years now as a result of early participation in our trials. I hope that by treating the most appropriate patients, earlier Air Max 82 in their disease, we can offer them much better outcomes in the future."

engineered virus carrying an anticancer gene, ups survival in late stage head/neck cancer. It may work in other cancers, too.

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Advexin carries the p53 anticancer gene. The p53 gene is the body's natural mechanism for stopping tumor growth. During many kinds of cancer, mutant versions of p53 arise. All rightsUsing a doctored version of a common cold virus, Advexin carries a new p53 gene into tumor cells. It causes these cells to self destruct and also has a bystander effect that reins in neighboring Air Max 95 Limited Edition

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That's why John Nemunaitis, MD, medical director of Dallas' Mary Crowley Center, and colleagues at Introgen Therapeutics Inc. tested the treatment in patients with late stage head and neck cancer. It's a deadly cancer, but one that's accessible to direct injection.

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